Application of hepatocyte forming agent self-secretion circulation in diagnosis and treatment of liver cancer


Application Number  00128248 Application Date  2000.12.14
Publication Number  1358541 Publication Date  2002.07.17
Priority Information    
International
Classification
 A61K38/19;A61P35/00;G01N33/574;G01N33/68  
Applicant(s) Name  Inst. of Radiomedicine, Military medical Science Academy of PLA  
Address    
Inventor(s) Name  He Fuchu;Li Yong;Xing Guichun  
Patent Agency Code  00000 Patent Agent  
AbstractThe present invention relates to the application of hepatocytopoietins self-secretion circulation for diagnosing and curnig liver cancer. It shows that liver cancer cell expresses hepatocytopoietins and its specific receptor, and can secrete hepatocytopoietins into cell culture fluid, besides, the hepatocytopoietins possesses proliferation stimulatory function to primary cultured liver cell and liver cancer cell, the conditioned medium of liver cancer cell also possesses pruliferation stimulatory function to its self-body, and the hepatocytopoietins neutralizing antibdoy can reduce this function, and can partially inhibit autonomous growth of liver cancer cell.