Aqueous soluble steroid compound alkaloid salt, preparation process and medicinal composition containing same


Application Number  00129507 Application Date  2000.09.29
Publication Number  1345727 Publication Date  2002.04.24
Priority Information    
International
Classification
 A61K31/575;A61P9/10;A61P31/12;C07J9/00  
Applicant(s) Name  Shandong Luye Pharmaceutical Co., Ltd.  
Address    
Inventor(s) Name  Liu Dianbo;Cong Xiaodong;Sun Shengmao  
Patent Agency Code  00000 Patent Agent  
AbstractThe present invention relates to sterides alkaloid water soluble salts, their preparation method and compositions containing them. Said invention also provides their general formulae. These alkaloid mainly can be used for curing angiocardiopathy and cerebrovascular diseases, but they have the defects of poor solubility and low bioavailability. In said invention, they react with acid to produce water soluble salts, raiser ther water solubility so as to raise their bioavailability and therapeutic effect.