Chitoser ester and its preparing process and application


Application Number  00129362 Application Date  2000.11.27
Publication Number  1355255 Publication Date  2002.06.26
Priority Information    
International
Classification
 A61P9/10;C07H3/06;C08B37/02  
Applicant(s) Name  Qingdao Oceanology Univ  
Address    
Inventor(s) Name  Xu Jiamin;Li Yingxia;Lu Zhihua  
Patent Agency Code  37201 Patent Agent  cui qingchen
AbstractA chitose ester (3-O-substituent-6-O-substituent-beta-1,4-D-2-amino-2-deoxy-glucosan) in prepared through suspending chitoamine in isopropanol, adding NaOH for reaction, then adding the isopropanol solution of chlorophytanic acid by several times, filtering to obtain the resultant, dewatering, vacuum drying, adding intermediate to sulfating reagent, washing the resultant until pH=4, dissolving in water, filtering, deposition in alcohol, repeated washing, dewatering and finally, vacuum drying. It can be used to prepare the medicine for preventing and treating cardiovascular and cerebrovascular diseases.