Efficient expression system of genetically engineered antibody eukaryon and its preparing process and application


Application Number: 00108065
Application Date: 2000.06.09
Publication Number: 1328157
Publication Date: 2001.12.26
Priority Information:
International: C12N15/79;C12N15/13;C12N15/52;C12N15/54;C07K16/00
Applicant(s) Name: Inst of Tumors, Tumor Hospital, Chinese Academy of Medical Sciences
Address:
Inventor(s) Name: Yang Zhihua;Ran Yuliang
Patent Agency Code: 72002
Patent Agent: lin xiaogong
Abstract The present invention relates to a process for preparing an efficient expression system of genetically engineered antibody eukaryou, a resultant efficient expression system pYR-GKES which includes 8 individual clone carriers and expression carrier, and the application of said expression system in preparing chimeric antibody, modified antibody, fully humanized antibody, etc.