Enzyme resolution process for prepairng chiral-trans-chrysanthemum monocarboxylic acid

Application Number: 00110661
Application Date: 2000.07.13
Publication Number: 1334344
Publication Date: 2002.02.06
Priority Information:
International: C12P41/00;C07C61/37
Applicant(s) Name: Dalian Inst of Chemicophysics, Chinese Academy of Sciences
Inventor(s) Name: Shao Changping;Liu Ren;Pan Guizhi
Patent Agency Code: 21002
Patent Agent: zhang chen
Abstract An enzyme resolution process for preparing chiral R(+) trans-chrysanthemum monocarboxylic acid uses the racemized (+/-)-chrysanthemum monocarboxylate as raw material and the esterase as catalyst, and includes such steps as adding particular additive chosen from oligose, polyose and non-ionic surfactant, and asymmetric hydrolysis reaction under the action of said catalyst. Its advantages are high desired product selectivity and high feasibility.