Humanized antibody with specificity to HBV surface antigen PRE-S1 and its producing process

Application Number: 00107535
Application Date: 2000.05.17
Publication Number: 1322762
Publication Date: 2001.11.21
Priority Information:
International: C07K16/18;C12N15/12;C12N15/63;A61K39/395;A61P31/12;A61P1/16
Applicant(s) Name: Korea Advanced Inst. of Science and Technology
Inventor(s) Name: Hong Hyojung;Ryu Chunjvi;Ho Hyangsok
Patent Agency Code: 11021
Patent Agent: hu jiaoyu
Abstract The present invention relates to humanized antibody with specificity to HBV surface antigen pre-S1, and it exhibits affinity similar to mouse monoclonal antibody and obviously lower immunogenicity owing to less amino acid residue from mouse. Therefore, the humanized antibody of the present invention may be used in preventing HBV infection and treating hepatitis B.