Low sustituted ethylene-lactic cellulose and solid preparation

Application Number: 00108581
Application Date: 2000.05.18
Publication Number: 1273861
Publication Date: 2000.11.22
Priority Information: 1999/5/18 JP 136788/1999
International: A61K47/38
Applicant(s) Name: Shin-Etsu Chemical Co., Ltd.
Inventor(s) Name: Kobubo Hirokyo
Patent Agency Code: 11038
Patent Agent: yang hongjun
Abstract The present invention can improve the wettability and significantly shorten the disintegration time of a solid formulation even in the same amount added and formulating composition as those of a conventional formulation by using a specific hydroxypropyl cellulose having a low degree of substitition. A hydroxypropyl cellulose having a low degree of substitution of 0.04-0.1 average number of substituted mol of hydroxypropoxyl groups based on the glucose unit is used.