| Application Number | 00129555 | Application Date | 2000.10.09 |
| Publication Number | 1290707 | Publication Date | 2001.04.11 |
| Priority Information | |||
| International Classification |
C07H19/20 | ||
| Applicant(s) Name | Qinghua Univ. | ||
| Address | |||
| Inventor(s) Name | Zhao Yufen;Miao Zhiwei;Han Bo | ||
| Patent Agency Code | 11201 | Patent Agent | luo wenqun |
| AbstractNucleoside 5'-thiiophosphoryl amino acid ester compound is prepared through the processes of dissolving thiophosphoryl trichloride in dried tetrahydrofuran, addition of carbamate hydrochloride through stirring, dripping acid binding agent to react, filtering, rotating distillation to eliminate solvent and other low boiling point matters, hydrolysis in ammonia water and final silica gel chromatography. The compound of the present invention may be used in developing medicine with antiviral, antitumor and HIV resisting activity. | |||