Process for separating compound anisodus luridus from plant Artemisia annua

Application Number: 00108330
Application Date: 2000.03.30
Publication Number: 1315324
Publication Date: 2001.10.03
Priority Information:
International: C07D311/58
Applicant(s) Name: Council of Scientific & Industrial Research
Inventor(s) Name: D.C. Jeen;N. Gooputa;M.M. Buhakoony
Patent Agency Code: 11038
Patent Agent: guo jianxin
Abstract A process for separating the scopoletin from Artemisia annua and other plants includes such steps as extracting the powder of said plant in hydrous acetonitrile solvent in ratio of 1:5 for 6-8 hr, vacuum concentrating, dissolving the concentrated liquid extract in non-polar halogenating solvent, drying on anhydrous sodium sulfate, evaporating, crystallizing in methanol, filtering, concentrating the filtrate, chromatographic analysis on silica gel, diluting the scopoletin with the mixed solution of chloroform and methanol, and crystallizing.