Producing influenza killed vaccine by sepharose 4FF column chromatography technology

Application Number: 00109399
Application Date: 2000.06.01
Publication Number: 1326939
Publication Date: 2001.12.19
Priority Information:
International: C07K1/16;C07K14/005;A61K39/12;A61P31/16
Applicant(s) Name: Changsheng Industry Co., Ltd., Changchun
Inventor(s) Name: Zhu Changlin;Gao Junfang;Wu Xiaoli
Patent Agency Code: 00000
Patent Agent:
Abstract Up to now, influenza killed vaccine is prepared through expensive and complicated cane sugar gradient density centrifugation technology. The present invention prepares through Sepharose AFF column chromatographic process, which is low in cost and relatively simple and can produce influenza killed vaccine with high safety and excellent immunogenicity.