Simulating moving-bed chromatographic separation process of carbogemeprost

Application Number: 00110348
Application Date: 2000.04.19
Publication Number: 1318423
Publication Date: 2001.10.24
Priority Information:
International: B01D15/08
Applicant(s) Name: Anshan Iron &. Steel College
Inventor(s) Name: Lin Bingchang;Gu Yushan;Zhang Jiayuan
Patent Agency Code: 00000
Patent Agent:
Abstract The present invention solves the problems of high solvent and stuffing consumption, limited purity, etc. during batch treatment, improves operation environment and reises automatic production level and features that the adoption of simulating moving-bed chromatographic system with reverse silica gel as stuffing and methanol-water mixture as flowing phase. The material is decontaminated before entering to the simulating moving-bed chromatographic system and the product is concentrated, recrystallized to obtain purity over 90%.