Synthesis of ketonic acid lactone amino carbomate antibiotics

Application Number  00129252 Application Date  2000.09.29
Publication Number  1289778 Publication Date  2001.04.04
Priority Information   1999/9/29 US 60/156,554  
Applicant(s) Name  Pfizer Products Inc.  
Inventor(s) Name  Kaneka Takashi;R.W. MacLeokelin;W.T. MacMillan  
Patent Agency Code  11105 Patent Agent  wu xiaonan
AbstractThe invention relates to a method of preparing a macrolide antibiotic of the formula (15) wherein R<1>, R<2>, R<3>, R<4>, R<5> are defined above. These antibiotics are useful as antibacterial and antiprotozoal agents in mammals, including man, as well as in fish and birds. The invention also includes novel compounds made by the preparation of the macrolide antibiotic.