Tag Archives: INHIBITOR

Inhibitor used as antioxygen and 5-lipoxygenase, and anti-inflammatory non-steroid carboxylic ester and amide of non-steroid anti-inflammatory agent

Application Number  00128522 Application Date  1995.12.21 Publication Number  1318544 Publication Date  2001.10.24 Priority Information   1994/12/23 US 08/362,718; 1995/6/7 US 08/472,445   International Classification  C07D311/72;C07D307/80;A61K31/343;A61K31/352;A61P39/06   Applicant(s) Name  Alcon Laboratories Co.   Address     Inventor(s) Name  M. Helberg;G. Graph;D.A. Garmacher   Patent Agency Code  11038 Patent Agent  chen wenbeng AbstractThe compounds of the present… Read More »

Method for preparing neuraminidase inhibitor RO-64-0796

Application Number: 00118139Application Date: 2000.06.09Publication Number: 1277957Publication Date: 2000.12.27Priority Information: 2000/2/21 EP 00103588.0; 1999/6/11 EP 99111418.2International: C07C211/09;C07C211/01;C07C229/46;C07C215/02;C07C311/36Applicant(s) Name: F. Hoffmann-La Roche & Co. AGAddress: Inventor(s) Name: M. Kapf;R. TrusatiPatent Agency Code: 11038Patent Agent: du jingyangAbstract The invention provides a multistep process for preparing 1,2-diamino compounds of formulawherein R1, R1', R2, R2', R3 and R4 have… Read More »

Polypeptide-human Kazal-type inhibitor 15 and polynucleotide for coding it

Application Number: 00115891Application Date: 2000.05.26Publication Number: 1325887Publication Date: 2001.12.12Priority Information: International: A61K31/7088;A61K38/16;A61K38/17;A61K39/395;A61P7/00;A61P31/00;A61P31/18;A61P35/00;A61P37/00;C07H21/00;C07K14/00;C07K14/435;C07K16/00;C07K16/18;C12N15/10;C12N15/11;C12N15/12;C12N15/63;C12N15/64;C12P21/00;C12Q1/68;G01N33/68Applicant(s) Name: Bode Gene Development Co Ltd, ShanghaiAddress: Inventor(s) Name: Mao Yumin;Xie YiPatent Agency Code: 00000Patent Agent: Abstract A novel polypeptide-human Kazal-type inhibitor 15, the polynucleotide for coding it, the process for preparing said polypeptide by DNA recombination, the application of said polypeptide in… Read More »

Giant well bombinator proteinase inhibitor and its prepn. and pharmaceutical application

Application Number: 00122416Application Date: 2000.07.29Publication Number: 1336385Publication Date: 2002.02.20Priority Information: International: A61K38/57;A61P1/04;A61P1/18;C07K1/14;C07K14/435Applicant(s) Name: Kunming Inst. of Zoology, Chinese Academy of SciencesAddress: Inventor(s) Name: Zhang Yun;Lai Ren;Zheng YongtangPatent Agency Code: 53200Patent Agent: yang hongzhenAbstract The present invnetion invention relates to large puling toad protease inhibitor, it is a single chain serine protease inhibitor, obtained from said… Read More »

Polypeptide-human kazal-type inhibitor 11 and polynucleotide for coding it

Application Number: 00115897Application Date: 2000.05.26Publication Number: 1325889Publication Date: 2001.12.12Priority Information: International: A61K31/7088;A61K38/16;A61K38/17;A61K39/395;A61P7/00;A61P31/00;A61P31/18;A61P35/00;A61P37/00;C07H21/00;C07K14/00;C07K14/435;C07K16/00;C07K16/18;C12N15/10;C12N15/11;C12N15/12;C12N15/63;C12N15/64;C12P21/00;C12Q1/68;G01N33/68Applicant(s) Name: Bode Gene Development Co Ltd, ShanghaiAddress: Inventor(s) Name: Mao Yumin;Xie YiPatent Agency Code: 00000Patent Agent: Abstract A novel polypeptide-human Kazal-type inhibitor 11, the polynucleotide for coding it, the process for preparing said polypeptide by DNA recombination, the application of said polypeptide in… Read More »

Preparation of human vasal endothelial cell growth inhibitor and its application in tumor angiogenesis resisting treatment

Application Number: 00123041Application Date: 2000.09.29Publication Number: 1288897Publication Date: 2001.03.28Priority Information: International: C07K14/475;C12N15/11;C12P21/00;A61P35/00Applicant(s) Name: Weixing Biological Product Inst. (Co., Ltd.), LiaoningAddress: Inventor(s) Name: Li Zhongyi;Chen Linsheng;Liu JiangqiuPatent Agency Code: 21115Patent Agent: sun jixiuAbstract The present invention belongs to the field of gene engineering technology, and relates to a preparation method of human recombinative vascular endotheliocytopoiesis suppressor… Read More »

New polypeptide-human death inhibitor 22 and polynucleotide for encoding such polypeptide

Application Number: 00116341Application Date: 2000.06.05Publication Number: 1326967Publication Date: 2001.12.19Priority Information: International: A61K31/7088;A61K38/16;A61K38/17;A61K39/395;A61P7/00;A61P31/00;A61P31/18;A61P35/00;A61P37/00;C07H21/00;C07K14/00;C07K14/435;C07K16/00;C07K16/18;C12N15/10;C12N15/11;C12N15/12;C12N15/63;C12N15/64;C12P21/00;C12Q1/68;G01N33/68Applicant(s) Name: Bode Gene Development Co., Ltd., ShanghaiAddress: Inventor(s) Name: Mao Yumin;Xie YiPatent Agency Code: 00000Patent Agent: Abstract The present invention discloses one new kind of polypeptide-human death inhibitor 22, polynucleotide for encoding this polypeptide and DNA recombination process to produce the polypeptide. The… Read More »

Polypeptide-human trypsin inhibitor 10.12 and polynucleotide for coding it

Application Number: 00125145Application Date: 2000.09.12Publication Number: 1342685Publication Date: 2002.04.03Priority Information: International: A61K31/7088;A61K38/16;A61K38/17;A61K39/395;A61P7/00;A61P31/00;A61P31/18;A61P35/00;A61P37/00;C07H21/00;C07K14/00;C07K14/435;C07K16/00;C07K16/18;C12N15/10;C12N15/11;C12N15/12;C12N15/63;C12N15/64;C12P21/00;C12Q1/68;G01N33/68Applicant(s) Name: Bode Gene Development Co Ltd, ShanghaiAddress: Inventor(s) Name: Mao Yumin;Xie YiPatent Agency Code: 00000Patent Agent: Abstract A novel polypeptide-human tyrpsin inhibitor 10.12, the polynucleotide for coding it, the process for preparing the said polypeptide by DNA recombination technique, the application of the… Read More »

Polypeptide-human wither inhibitor 38.06 and polynucleotide for coding it

Application Number: 00116421Application Date: 2000.06.12Publication Number: 1328021Publication Date: 2001.12.26Priority Information: International: A61K31/7088;A61K38/16;A61K38/17;A61K39/395;A61P7/00;A61P31/00;A61P31/18;A61P35/00;A61P37/00;C07H21/00;C07K14/00;C07K14/435;C07K16/00;C07K16/18;C12N15/10;C12N15/11;C12N15/12;C12N15/63;C12N15/64;C12P21/00;C12Q1/68;G01N33/68Applicant(s) Name: Bode Gene Development Co Ltd, ShanghaiAddress: Inventor(s) Name: Mao Yumin;Xie YiPatent Agency Code: 00000Patent Agent: Abstract A novel polypeptide-human wither inhibitor 38.06, the polynucleotide for coding it, the process for preparing said polypeptide by DNA recombination, the application of said polypeptide in… Read More »

Method for preparing 5-lipooxygenase inhibitor having changeable heterocycle system

Application Number: 00126408Application Date: 2000.08.30Publication Number: 1286250Publication Date: 2001.03.07Priority Information: 1999/8/31 US 60/151,615International: C07D309/08;C07D405/12Applicant(s) Name: Pfizer Products, Inc.Address: Inventor(s) Name: T. Noris;J.F. Rambert;M.E. NatoPatent Agency Code: 11038Patent Agent: li huayangAbstract The invention describes a intermediate of tetrahydro-4- 3-(4-fluorophenyl)thiophenyl-2H-pyran-4-carboxamide of the formula (2.0.0), as well as its use in a process of preparing 5-lipoxygenase inhibitors of… Read More »

Polypeptide-cytokine signal inhibitor SOCS-5-29 and polynucleotide for coding it

Application Number: 00116831Application Date: 2000.06.28Publication Number: 1331096Publication Date: 2002.01.16Priority Information: International: A61K31/7088;A61K38/16;A61K38/17;A61K39/395;A61P7/00;A61P31/00;A61P31/18;A61P35/00;A61P37/00;C07H21/00;C07K14/00;C07K14/435;C07K16/00;C07K16/18;C12N15/10;C12N15/11;C12N15/12;C12N15/63;C12N15/64;C12P21/00;C12Q1/68;G01N33/68Applicant(s) Name: Bode Gene Development Co Ltd, ShanghaiAddress: Inventor(s) Name: Mao Yumin;Xie YiPatent Agency Code: 00000Patent Agent: Abstract A novel polypeptide-cytokine signal inhibitor SOCS-5-29, the polynucleotide for coding it, the process for preparing the said polypeptide by DNA recombination, the application of the said… Read More »

Method for preparing 5-lipooxygenase inhibitor having changeable heterocycle system

Application Number: 00126409Application Date: 2000.08.30Publication Number: 1286251Publication Date: 2001.03.07Priority Information: 1999/8/31 US 60/151,610International: C07D309/08;C07D405/12Applicant(s) Name: Pfizer Products, IncAddress: Inventor(s) Name: T. Noris;M.E. NatoPatent Agency Code: 11038Patent Agent: tang weijieAbstract A process is described for preparing a compound of Formula (1.3.0). Please to see the concrete description in the explain.

Polypeptide-human DNA-dependent RNA polymerase AC40 subunit inhibitor 9.68 and polynucleotide for coding it

Application Number: 00116951Application Date: 2000.06.30Publication Number: 1331298Publication Date: 2002.01.16Priority Information: International: A61K38/43;C07K16/40;C12N9/00;C12N15/52;C12N15/63;C12Q1/25;C12Q1/68Applicant(s) Name: Bode Gene Development Co Ltd, ShanghaiAddress: Inventor(s) Name: Mao Yumin;Xie YiPatent Agency Code: 00000Patent Agent: Abstract A novel polypeptide-human DNA-dependent RNA polymerase AC40 subunit inhibitor 9.68, the polynucleotide for coding it, the process for preparing the said polypeptide by DNA recombination, the… Read More »

Method of preparing 5-lipoxidase inhibitor possessing different heterocyclic ring system

Application Number: 00126870Application Date: 2000.08.30Publication Number: 1291609Publication Date: 2001.04.18Priority Information: 1999/8/31 US 60/151611International: C07D405/12Applicant(s) Name: Pfizer Products Inc.Address: Inventor(s) Name: T. Noris;M.E. Henato;J.F. LanburtPatent Agency Code: 72001Patent Agent: zhong shouqiAbstract Disclosed is a method for preparing compounds of formula (1.3.0) (see specification) comprising: establishing a reaction mixture in non-protonicsolvent, in the presence of a strong… Read More »

New polypeptide-human plasminogen activator inhibitor 2-15.95 and polynuceotide for encoding such polypeptide

Application Number: 00127319Application Date: 2000.11.10Publication Number: 1352139Publication Date: 2002.06.05Priority Information: International: A61K31/7088;A61K38/16;A61K38/17;A61K39/395;A61P7/00;A61P31/00;A61P31/18;A61P35/00;A61P37/00;C07H21/00;C07K14/00;C07K14/435;C07K16/00;C07K16/18;C12N15/10;C12N15/11;C12N15/12;C12N15/63;C12N15/64;C12P21/00;C12Q1/68;G01N33/68Applicant(s) Name: Bode Gene Development Co., Ltd., ShanghaiAddress: Inventor(s) Name: Mao Yumin;Xie YiPatent Agency Code: 00000Patent Agent: Abstract The present invention discloses a new kind of polypeptide, human plasmingen activator inhibitor 2-15.95, polynucleotide for encoding this polypeptide and DNA recombination process to produce the… Read More »

Polypeptide-human DNA-dependent RNA polymerase AC40 subunit inhibitor 9.13 and polynucleotide for coding it

Application Number: 00116959Application Date: 2000.06.30Publication Number: 1331299Publication Date: 2002.01.16Priority Information: International: A61K38/43;C07K16/40;C12N9/00;C12N15/52;C12N15/63;C12Q1/25;C12Q1/68Applicant(s) Name: Bode Gene Development Co Ltd, ShanghaiAddress: Inventor(s) Name: Mao Yumin;Xie YiPatent Agency Code: 00000Patent Agent: Abstract A novel polypeptide-human DNA-dependent RNA polymerase AC40 subunit inhibitor 9.13, the polynucleotide for coding it, the process for preparing the said polypeptide by DNA recombination, the… Read More »

New polypeptide-human plasminogen activator inhibitor 2-13.31 and polynucleotide for encoding such polypeptide

Application Number: 00127169Application Date: 2000.11.02Publication Number: 1352072Publication Date: 2002.06.05Priority Information: International: A61K31/7088;A61K38/16;A61K38/17;A61K39/395;A61P7/00;A61P31/00;A61P31/18;A61P35/00;A61P37/00;C07H21/00;C07K14/00;C07K14/435;C07K16/00;C07K16/18;C12N15/10;C12N15/11;C12N15/12;C12N15/63;C12N15/64;C12P21/00;C12Q1/68;G01N33/68Applicant(s) Name: Bode Gene Development Co., Ltd., ShanghaiAddress: Inventor(s) Name: Mao Yumin;Xie YiPatent Agency Code: 00000Patent Agent: Abstract The present invention discloses a new kind of polypeptide, human plasminogen activator inhibitor 2-13.31, polynucleotides for encoding this polypeptide and DNA recombination process to produce the… Read More »

New polypeptide-human plasminogen activator inhibitor 2-9 and polynucleotide for coding said polypeptide

Application Number: 00111835Application Date: 2000.03.02Publication Number: 1311226Publication Date: 2001.09.05Priority Information: International: A61K31/7088;A61K38/16;A61K38/17;A61K39/395;A61P7/00;A61P31/00;A61P31/18;A61P35/00;A61P37/00;C07H21/00;C07K14/00;C07K14/435;C07K16/00;C07K16/18;C12N15/10;C12N15/11;C12N15/12;C12N15/63;C12N15/64;C12P21/00;C12Q1/68;G01N33/68Applicant(s) Name: Bode Gene Development Co., Ltd., ShanghaiAddress: Inventor(s) Name: Mao Yumin;Xie YiPatent Agency Code: 00000Patent Agent: Abstract This invention discloses a new polypeptide-human fibrolysosome activator inhibitor 2-9, polynucleotide for coding this polypeptide and the method for producing this polypeptide through DNA recombination technique.… Read More »

Novel polypeptide–huan nervous serinje protease inhibitor (PI12) 83.27 and polynucleotide for encoding said polypeptide

Application Number: 00117032Application Date: 2000.07.07Publication Number: 1333249Publication Date: 2002.01.30Priority Information: International: A61K31/7088;A61K38/16;A61K38/17;A61K39/395;A61P7/00;A61P31/00;A61P31/18;A61P35/00;A61P37/00;C07H21/00;C07K14/00;C07K14/435;C07K16/00;C07K16/18;C12N15/10;C12N15/11;C12N15/12;C12N15/63;C12N15/64;C12P21/00;C12Q1/68;G01N33/68Applicant(s) Name: Shanghai Bode Gene Development Co., Ltd.Address: Inventor(s) Name: Mao Yumin;Xie YiPatent Agency Code: 00000Patent Agent: Abstract The present invention discloses a novel polypeptide-human nervous serine protease inhibitor (PI12) 83.27, polynucleotide for coding said polypeptide and method for producing this polypeptide by DNA… Read More »

New polypeptide-human plasminogen activator inhibitor 2-9.9 and polynucleotide for encoding such polypeptide

Application Number: 00127230Application Date: 2000.11.06Publication Number: 1352101Publication Date: 2002.06.05Priority Information: International: A61K31/7088;A61K38/16;A61K38/17;A61K39/395;A61P7/00;A61P9/10;A61P31/00;A61P31/18;A61P35/00;A61P37/00;A61P43/00;C07H21/00;C07K14/00;C07K14/435;C07K16/00;C07K16/18;C12N15/10;C12N15/11;C12N15/12;C12N15/63;C12N15/64;C12P21/00;C12Q1/68;G01N33/68Applicant(s) Name: Bode Gene Development Co., Ltd., ShanghaiAddress: Inventor(s) Name: Mao Yumin;Xie YiPatent Agency Code: 00000Patent Agent: Abstract The present invention dislcoses a new kind of polypeptide, human plasminogen activator inhbitor 2-9.9, polynucleotides for encoding this polypeptide and DNA recombination process to produce the… Read More »

Inhibitor for preventing and eliminating plant viruses

Application Number: 00113839Application Date: 2000.06.14Publication Number: 1327740Publication Date: 2001.12.26Priority Information: International: A01N59/20Applicant(s) Name: Hailang Chemical Co Ltd, XianAddress: Inventor(s) Name: Zhang Qinfu;An Derong;Ma ChiPatent Agency Code: 61100Patent Agent: huo zhongniuAbstract An inhibitor of plant viruses such as cucumber mosaic virus (CMV) and tobacco mosaic virus (TMV) contains virazole (0.02-2.0 wt.%), copper sulfate (0.5-15), zinc sulfate… Read More »

Process for preparing inhibitor of tobacco buds

Application Number: 00117313Application Date: 2000.08.08Publication Number: 1286024Publication Date: 2001.03.07Priority Information: International: A01N33/18Applicant(s) Name: Inst of Plant Protection, Guandong Academy of Agriculatural SciencesAddress: Inventor(s) Name: Tian Xingshan;Qiu Miaowen;Chen YongmingPatent Agency Code: 44201Patent Agent: luo guanxiangAbstract A tobacco bud inhibitor "Yanyajing" is prepared through proportioning, dissolving trifluralin in solvent, adding emulsifier and machine oil and stirring. It… Read More »

New polypeptide-human plasminogen activator inhibitor 2-12.65 and polynucleotide for encoding such polypeptide

Application Number: 00127255Application Date: 2000.11.06Publication Number: 1352119Publication Date: 2002.06.05Priority Information: International: A61K31/7088;A61K38/16;A61K38/17;A61K39/395;A61P7/00;A61P31/00;A61P31/18;A61P35/00;A61P37/00;C07H21/00;C07K14/00;C07K14/435;C07K16/00;C07K16/18;C12N15/10;C12N15/11;C12N15/12;C12N15/63;C12N15/64;C12P21/00;C12Q1/68;G01N33/68Applicant(s) Name: Bode Gene Development Co., Ltd., ShanghaiAddress: Inventor(s) Name: Mao Yumin;Xie YiPatent Agency Code: 00000Patent Agent: Abstract The present invention discloses a new kind of polypeptide, human plasminogen activator inhibitor 2-12.65, polynucleotides for encoding this polypeptide and DNA recombination process to produce the… Read More »

Polypeptide-human plasminogen activator inhibitor 2-27 and polynucleotide for coding it

Application Number: 00114916Application Date: 2000.03.15Publication Number: 1313331Publication Date: 2001.09.19Priority Information: International: A61K31/7088;A61K38/16;A61K38/17;A61K39/395;A61P7/00;A61P31/00;A61P31/18;A61P35/00;A61P37/00;C07H21/00;C07K14/00;C07K14/435;C07K16/00;C07K16/18;C12N15/10;C12N15/11;C12N15/12;C12N15/63;C12N15/64;C12P21/00;C12Q1/68;G01N33/68Applicant(s) Name: Bode Gene Development Co Ltd, ShanghaiAddress: Inventor(s) Name: Mao Yumin;Xie YiPatent Agency Code: 00000Patent Agent: Abstract A new polypeptide-human plasminogen activator inhibitor 2-27, the polynucleotide for coding it, the process for preparing said polypeptide by DNA recombination, the application of said polypeptide… Read More »

Salt as thrombin inhibitor

Application Number: 00118039Application Date: 2000.05.10Publication Number: 1279236Publication Date: 2001.01.10Priority Information: 1999/5/10 DE 19921345.3; 1999/10/1 DE 19947479.6International: A61K31/397;A61K31/40;A61K31/41;A61K31/4427;A61K31/505;A61K31/519;A61P7/02;C07D401/14;C07D403/12;C07D417/12;C07D417/14;C07D419/12;C07D419/14;C07D487/04Applicant(s) Name: BASF AGAddress: Inventor(s) Name: B. ScheffelPatent Agency Code: 72001Patent Agent: wang jihaoAbstract The invention relates to compounds of the general formula I, the tautomers and stereoisomers thereof, wherein HX is optionally substituted once or twice by methyl,… Read More »

New polypeptide-alpha-1 inhibitor III-10.67 and polynucleotide for encoding such polypeptide

Application Number: 00127279Application Date: 2000.11.06Publication Number: 1352017Publication Date: 2002.06.05Priority Information: International: A61K31/7088;A61K38/16;A61K38/17;A61K39/395;A61P7/00;A61P31/00;A61P31/18;A61P35/00;A61P37/00;C07H21/00;C07K14/00;C07K14/435;C07K16/00;C07K16/18;C12N15/10;C12N15/11;C12N15/12;C12N15/63;C12N15/64;C12P21/00;C12Q1/68;G01N33/68Applicant(s) Name: Bode Gene Development Co., Ltd., ShanghaiAddress: Inventor(s) Name: Mao Yumin;Xie YiPatent Agency Code: 00000Patent Agent: Abstract The present invention discloses a new kind of polypeptide, alpha-1 inhibitor III-10.67, polynucleotides for encoding this polypeptide and DNA recombination process to produce the polypeptide. The… Read More »

New polypeptide-human plasminogen activator inhibitor 10 and polynucleotide for coding such polypeptide

Application Number: 00115019Application Date: 2000.03.22Publication Number: 1314378Publication Date: 2001.09.26Priority Information: International: A61K31/7088;A61K38/16;A61K38/17;A61K39/395;A61P7/00;A61P31/00;A61P31/18;A61P35/00;A61P37/00;C07H21/00;C07K14/00;C07K14/435;C07K16/00;C07K16/18;C12N15/10;C12N15/11;C12N15/12;C12N15/63;C12N15/64;C12P21/00;C12Q1/68;G01N33/68Applicant(s) Name: Bode Gene Development Co., Ltd., ShanghaiAddress: Inventor(s) Name: Mao Yumin;Xie YiPatent Agency Code: 00000Patent Agent: Abstract The present invention discloses a new kind of polypeptide, human plasminogen activator inhibitor 10, polynucleotides for encoding this polypeptide and DNA recombinatino process to produce the… Read More »

Corrosion inhibitor of copper and its preparing process

Application Number: 00110308Application Date: 2000.04.11Publication Number: 1273283Publication Date: 2000.11.15Priority Information: International: C23F11/14Applicant(s) Name: Julong Inst. of Anti-Corrosion Technology, Shenyang CityAddress: Inventor(s) Name: Yu Fengqi;Yu Fengming;Yu JiePatent Agency Code: 21101Patent Agent: yang binAbstract A corrosion inhibitor of copper is prepared from benzotriazazole, industrial alcohol as solvent and water through proportional mixing and regulating pH value to… Read More »

Water injecting corrosion inhibitor for oil field

Application Number: 00109688Application Date: 2000.06.21Publication Number: 1277241Publication Date: 2000.12.20Priority Information: International: C09K15/04;F16L58/00Applicant(s) Name: Inst. of Petroleum Pipeline Material, China Petroleum & Natural Gas Corp.Address: Inventor(s) Name: Zhang Yufang;Lu MinxuPatent Agency Code: 11215Patent Agent: rong duizhangAbstract The corrosion inhibitor includes imidazoline quaternary ammonium derivative 70-80wt%, alkynol 5-10wt%, one kind of alkali metal iodide 3-5wt%, one other… Read More »

Corrosion inhibitor resisting CO2 corrosion for oil field

Application Number: 00109687Application Date: 2000.06.21Publication Number: 1277240Publication Date: 2000.12.20Priority Information: International: C09K15/04;F16L58/00Applicant(s) Name: Inst. of Petroleum Pipeline Material, China Petroleum & Natural Gas Corp.Address: Inventor(s) Name: Zhang Yufang;Lu MinxuPatent Agency Code: 11215Patent Agent: rong duizhangAbstract The corrosion inhibitor includes sulfur-containing imidazoline derivative 25-40wt%, alkyl phosphate 20-30wt%, alkynol 5-15wt%, non-ionic surfactant 10-20wt% and solvent 20-30wt%. It… Read More »