Carrier for expressing Chiense chicken pox virus vaccine strain

Application Number: 00103298
Application Date: 2000.03.23
Publication Number: 1268573
Publication Date: 2000.10.04
Priority Information:
International: A61K39/275;C12N15/64
Applicant(s) Name: Military Supply Univ., PLA
Inventor(s) Name: Jin Ningyi;Guo Zhiru;Fang Houhua
Patent Agency Code: 11246
Patent Agent: huang jiadun
Abstract The present invention provides 14 henpox virus 282 E4 strain reconstittion expression carrier, of which 8 are constituted by inserting two henpox virus promotors respectively into 282 E4 strain TK gene or 1.5 kbB fragment nonessential region. Take bacillus coli LacZ gene or green fluorescent protein gene as report gene and insert into 6 carrier of above mentioned expression carrier to construct another six Chinese henpox virus 282 E4 reconstitution expression carrier containing report gene. By using these expression carrier can obtain reconstituted virus for expressing different exogenous gene, these reconstituted virus can be used as vaccine for preventing and treating human, poultry and animal diseases.