Process for preparing marine conidae analgesic polypeptide

Application Number  00128525 Application Date  2000.11.24
Publication Number  1296012 Publication Date  2001.05.23
Priority Information    
International
Classification
 C07K14/435  
Applicant(s) Name  Biological Engineering Inst., Military Medical Science Academy of PLA  
Address    
Inventor(s) Name  Dai Qiuyun;Huang Peitang;Zhou Yanrong  
Patent Agency Code  11038 Patent Agent  chen wenbeng
AbstractA method for preparing active conidae polypeptide includes the steps of linear peptide synthesis, linear peptide folding and peptide purification, and is characterized by that the described linear peptide folding is implemented in the oxidation-reduction system in the presence of 0.1-2M sodium chloride or sodium sulfate. According to the invented method, it can obtain high-effective, high-activity conidae polypeptide, and is suitable for production on a large scale.